An organic-base catalyzed asymmetric 1,4-addition of tritylthiol to in situ generated aza-o-quinone methides at the H2O/DCM interface-Reference-Cited by-同舟云学术

An organic-base catalyzed asymmetric 1,4-addition of tritylthiol to in situ generated aza-o-quinone methides at the H2O/DCM interface

Published:2019 Issue:18 Volume:55 Page:2668-2671
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Liu Xianghui¹²³⁴⁵,Wang Kai¹²³⁴⁵,Guo Wengang¹²³⁴⁵,Liu Yan¹²³⁴⁵,Li Can¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Catalysis

2. Dalian Institute of Chemical Physics

3. Chinese Academy of Sciences

4. Dalian 116023

5. P. R. China

Abstract

Highly enantioselective organocatalytic Michael addition of tritylthiol to N-o-QM intermediates generated in situ at the H₂O/DCM interface is presented.

Funder

National Natural Science Foundation of China

Dalian Institute of Chemical Physics

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CC/C8CC09382B

Reference56 articles.

1. Applications of ortho-Quinone Methide Intermediates in Catalysis and Asymmetric Synthesis

2. ortho-Quinone Methides in Natural Product Synthesis

3. ortho-Quinone methide (o-QM): a highly reactive, ephemeral and versatile intermediate in organic synthesis

4. The Domestication of ortho-Quinone Methides

5. Recent Advances in Catalytic Asymmetric Reactions of o-Quinone Methides

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