Phosphine-catalyzed enantioselective and diastereodivergent [3+2] cyclization for the construction of oxetane dispirooxindole skeletons-Reference-Cited by-同舟云学术

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Phosphine-catalyzed enantioselective and diastereodivergent [3+2] cyclization for the construction of oxetane dispirooxindole skeletons

Published:2024 Issue: Volume: Page:
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Han Xiao¹,Hou Jie¹,Zhang Haiyan¹,Wang Zhen²^ORCID,Yao Weijun¹^ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering, Zhejiang Sci-Tech University, Hangzhou, 310018, P. R. China

2. School of Pharmaceutical Sciences and Chongqing Key Laboratory of Natural Drug Research, Chongqing University, Chongqing 401331, P. R. China

Abstract

Enationselective and diastereodivergent [3+2] cyclization of 3-oxetanone derived MBH carbonates with activated methyleneoxindole was realized, to construct oxetane dispirooxindole skeletons.

Funder

Natural Science Foundation of Zhejiang Province

Natural Science Foundation of Chongqing Municipality

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D4CC03610G

Reference47 articles.

1. Oxetanes: Recent Advances in Synthesis, Reactivity, and Medicinal Chemistry

2. Four-Membered Ring-Containing Spirocycles: Synthetic Strategies and Opportunities

3. Natural Products Containing the Oxetane and Related Moieties Present Additional Challenges for Structure Elucidation: A DU8+ Computational Case Study

4. Oxetane-containing metabolites: origin, structures, and biological activities

5. Plant antitumor agents. VI. Isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia

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