Doxorubicin-conjugated CuS nanoparticles for efficient synergistic therapy triggered by near-infrared light-Reference-Cited by-同舟云学术

Doxorubicin-conjugated CuS nanoparticles for efficient synergistic therapy triggered by near-infrared light

Published:2016 Issue:12 Volume:45 Page:5101-5110
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Bi Huiting¹²³⁴⁵,Dai Yunlu¹²³⁴⁵,Lv Ruichan¹²³⁴⁵,Zhong Chongna¹²³⁴⁵,He Fei¹²³⁴⁵,Gai Shili¹²³⁴⁵,Gulzar Arif¹²³⁴⁵,Yang Guixin¹²³⁴⁵,Yang Piaoping¹²³⁴⁵

Affiliation:

1. Key Laboratory of Superlight Materials and Surface Technology

2. Ministry of Education

3. College of Material Sciences and Chemical Engineering

4. Harbin Engineering University

5. Harbin

Abstract

A CuS–DOX NP drug delivery system was synthesized by conjugating carboxyl-functionalized copper sulfide nanoparticles (CuS NPs) and DOX through hydrazone bonds. The platform exhibits high in vitro and in vivo anti-cancer efficacy due to the combined chemo- and photothermal therapeutic effect upon 808 nm laser irradiation.

Funder

Natural Science Foundation of Heilongjiang Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/DT/C5DT04842G

Reference70 articles.

1. Surface Engineering of Iron Oxide Nanoparticles for Targeted Cancer Therapy

2. Recent Advances in Design and Fabrication of Upconversion Nanoparticles and Their Safe Theranostic Applications