Direct amidation of the phenylalanine moiety in short peptides via Pd-catalyzed C–H activation/C

Direct amidation of the phenylalanine moiety in short peptides via Pd-catalyzed C–H activation/C–N formation

Published:2015 Issue:1 Volume:2 Page:51-54
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Yang Mingyu¹²³⁴⁵,Jiang Xingyu¹²³⁴⁵,Shi Zhang-Jie¹²³⁴⁵

Affiliation:

1. Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education

2. College of Chemistry and Green Chemistry Center

3. Peking University

4. Beijing

5. China

Abstract

The direct amidation of dipeptides through direct aryl C–H transformation of the phenylalanine residue via Pd catalysis.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/QO/C4QO00282B

Reference49 articles.

1. Site-specific C-functionalization of free-(NH) peptides and glycine derivatives via direct C-H bond functionalization

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3. Chemical remodelling of cell surfaces in living animals

4. Chemistry in living systems

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