High-throughput acoustofluidic fabrication of tumor spheroids

Author:

Chen Bin12345,Wu Yue1234,Ao Zheng1234,Cai Hongwei1234,Nunez Asael1234,Liu Yunhua67849,Foley John1011734,Nephew Kenneth1011734,Lu Xiongbin67849,Guo Feng12349ORCID

Affiliation:

1. Department of Intelligent Systems Engineering

2. Indiana University

3. Bloomington

4. USA

5. Department of Laboratory Medicine

6. Department of Medical and Molecular Genetics

7. Indiana University School of Medicine

8. Indianapolis

9. Melvin and Bren Simon Cancer Center

10. Cell, Molecular and Cancer Biology Program

11. Medical Sciences

Abstract

Three-dimensional (3D) culture of multicellular spheroids, offering a desirable biomimetic microenvironment, is appropriate for recapitulating tissue cellular adhesive complexity and revealing a more realistic drug response.

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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