Fluorescent detection of point mutation via ligase reaction assisted by quantum dots and magnetic nanoparticle-based probes
Author:
Affiliation:
1. Department of Genetics
2. Faculty of Sciences
3. University of Isfahan
4. Iran
5. Nanomedicine Group
6. Immunogenetics Research Center
7. Mazandaran University of Medical Sciences
8. Sari
Abstract
A nanodiagnostic genotyping method was presented for point mutation detection directly in human genomic DNA based on ligase reaction coupled with quantum dots and magnetic nanoparticle-based probes.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA03767H
Reference56 articles.
1. Single Quantum Dot Analysis Enables Multiplexed Point Mutation Detection by Gap Ligase Chain Reaction
2. Detection of four β-thalassemia point mutations in Iranians using a PCR-ELISA genotyping system
3. Genotyping Technologies for Genetic Research
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