Electrochemical detection of glycan and protein epitopes of glycoproteins in serum

Author:

Shah Alok K.1234,Hill Michelle M.1234,Shiddiky Muhammad J. A.5624,Trau Matt5624

Affiliation:

1. The University of Queensland Diamantina Institute

2. The University of Queensland

3. Translational Research Institute

4. , Australia

5. Australian Institute for Bioengineering and Nanotechnology (AIBN)

6. Corner College and Cooper Roads (Bldg 75)

Abstract

We report electrochemical interrogation of glycan and protein epitopes of the glycoprotein chicken ovalbumin spiked in diluted serum using SNA lectin and anti-ovalbumin antibody.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Reference34 articles.

1. A. Varki and H. H.Freeze , in Essentials of Glycobiology , ed. A. Varki , R. D. Cummings , J. D. Esko , H. H. Freeze , P. Stanley , C. R. Bertozzi , G. W. Hart and M. E.Etzler , Cold Spring Harbor (NY) , 2nd edn, 2009

2. Glycans as cancer biomarkers

3. Automated immunoassay system for AFP–L3% using on-chip electrokinetic reaction and separation by affinity electrophoresis

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