Promoting high T2 contrast in Dy-doped MSNs through Curie effects

Author:

Ellis Connor M.1ORCID,Pellico Juan12ORCID,Young Liam A. J.34ORCID,Miller Jack345ORCID,Davis Jason J.1ORCID

Affiliation:

1. Department of Chemistry, University of Oxford, South Parks Road, Oxford, OX1 3QZ, UK

2. School of Biomedical Engineering & Imaging Sciences, King's College London, St. Thomas’ Hospital, London, SE1 7EH, UK

3. Department of Physiology, Anatomy & Genetics, University of Oxford, South Parks Road, Oxford, OX1 3PT, UK

4. Oxford Centre for Clinical Magnetic Resonance Research, Radcliffe Department of Medicine, University of Oxford, Level 0, John Radcliffe Hospital, Oxford, OX3 9DU, UK

5. Department of Physics, Clarendon Laboratory, Parks Road, Oxford, OX1 3PU, UK

Abstract

The dominant Curie effect underpinning relaxivity enhancements in T2 has been systematically tuned through paramagnetic loading density. This results in the optimisation of acquired MR image contrast, and facilitates effective high field imaging.

Funder

Novo Nordisk Fonden

British Heart Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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