A microfluidic device for TEM sample preparation-Reference-Cited by-同舟云学术

A microfluidic device for TEM sample preparation

Published:2020 Issue:22 Volume:20 Page:4186-4193
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Hauser Janosch¹²³⁴^ORCID,Kylberg Gustaf⁵⁶⁴,Colomb-Delsuc Mathieu⁵⁶⁴,Stemme Göran¹²³⁴,Sintorn Ida-Maria⁵⁶⁴,Roxhed Niclas¹²³⁴

Affiliation:

1. Division of Micro and Nanosystems

2. KTH Royal Institute of Technology

3. 10044 Stockholm

4. Sweden

5. Vironova AB

6. 11364 Stockholm

Abstract

We present a capillary-driven microfluidic single-use device that prepares a TEM grid with minimal user interaction. The user only initiates the sample preparation process, waits for about one minute and then collects the TEM grid, ready for imaging.

Funder

Stiftelsen för Strategisk Forskning

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/LC/D0LC00724B

Reference23 articles.

1. Negative staining and cryo-negative staining of macromolecules and viruses for TEM

2. Visualization of bionanostructures using transmission electron microscopical techniques

3. Has negative staining still a place in biomacromolecular electron microscopy?

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