Impact of aqueous micellar media on biocatalytic transformations involving transaminase (ATA); applications to chemoenzymatic catalysis-Reference-Cited by-同舟云学术

Impact of aqueous micellar media on biocatalytic transformations involving transaminase (ATA); applications to chemoenzymatic catalysis

Published:2022 Issue:16 Volume:24 Page:6172-6178
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Dussart-Gautheret Jade¹^ORCID,Yu Julie¹,Ganesh Krithika²,Rajendra Gaikwad²,Gallou Fabrice³^ORCID,Lipshutz Bruce H.¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA, 93106, USA

2. Anthem Biosciences Pvt. Ltd., #49, Canara bank road, Bommasandra Industrial Area, Bommasandra, Bengaluru-560099, Karnataka, India

3. Chemical & Analytical Development, Novartis Pharma AG, 4056 Basel, Switzerland

Abstract

Surfactant-enabled asymmetric ATA-catalyzed reductive aminations in aqueous buffered media are described, representative of the enhanced levels of conversion made possible by the presence of a nonionic surfactant in the water, thereby enabling 1-pot chemoenzymatic catalysis.

Funder

Novartis

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/GC/D2GC02002E

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