Multicomponent cascade reactions of HKAs: synthesis of highly functionalized 5H-chromeno[4,3-d]pyrimidines-Reference-Cited by-同舟云学术

Multicomponent cascade reactions of HKAs: synthesis of highly functionalized 5H-chromeno[4,3-d]pyrimidines

Published:2021 Issue:16 Volume:8 Page:4508-4513
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Fan Yun-Xiang¹²³⁴⁵,Cao Xin-Ling¹²³⁴⁵,Chen Li¹²³⁴⁵,Chen Yi-Hua¹²³⁴⁵,Yan Sheng-Jiao¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Medicinal Chemistry for Natural Resource (Yunnan University)

2. Ministry of Education; School of Chemical Science and Technology

3. Yunnan University

4. Kunming

5. P. R. China

Abstract

A novel protocol was developed for the construction of functionalized 5H-chromeno[4,3-d]pyrimidines from 3-formylchromones, heterocyclic ketene aminals, and amidine hydrochlorides via a novel cascade reaction involving ring-opening and 1,3-H shift reactions.

Funder

National Natural Science Foundation of China

Applied Basic Research Foundation of Yunnan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00666E

Reference32 articles.

1. Multicomponent Reactions , ed. J. P. Zhu and H. Bienayme , Wiley-VCH , Weinheim, Germany , 2005

2. Strategies for Innovation in Multicomponent Reaction Design