Novel crown-ether–methylenediphosphonotetrathioate hybrids as Zn(ii) chelators
Author:
Affiliation:
1. Department of Chemistry
2. Bar Ilan University
3. Ramat Gan
4. Israel
5. Department of Chemical Research Support
6. the Weizmann Institute of Science
7. Rehovot 76100
Abstract
A 13-membered methylenediphosphonotetrathioate–crown ether hybrid is a water-soluble, air-stable, high-affinity Zn(ii)-chelator, exhibiting selectivity to Zn(ii)vs.Mg(ii), Na(i), and Li(i).
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/DT/C5DT03935E
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1. Imaging free zinc levels in vivo – What can be learned?
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3. Out of the active site binding pocket for carbonic anhydrase inhibitors
4. Structure-based drug discovery of carbonic anhydrase inhibitors
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