Synthetic DNA binders for fluorescent sensing of thymine glycol-containing DNA duplexes and inhibition of endonuclease activity-Reference-Cited by-同舟云学术

Synthetic DNA binders for fluorescent sensing of thymine glycol-containing DNA duplexes and inhibition of endonuclease activity

Published:2023 Issue:40 Volume:59 Page:6088-6091
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Sato Yusuke¹^ORCID,Takaku Yoshihide¹,Nakano Toshiaki²^ORCID,Akamatsu Ken²,Inamura Dai¹,Nishizawa Seiichi¹^ORCID

Affiliation:

1. Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan

2. DNA damage chemistry research group, Institute for Quantum Life Science, National Institutes for Quantum Science and Technology, Kizugawa, 619-0215, Japan

Abstract

Dimethyllumazine (DML)-thiazole orange (TO) conjugates were developed for fluorescence sensing of thymine glycol (Tg)-containing DNAs based on the selective recognition of the A nucleobase opposite the Tg residue.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC01501G

Reference40 articles.

1. ROS and the DNA damage response in cancer

2. Thymidine glycol: the effect on DNA molecular structure and enzymatic processing

3. Dynamics of 5R-Tg Base Flipping in DNA Duplexes Based on Simulations─Agreement with Experiments and Beyond

4. Rapid Diagnosis of Prostate Cancer Disease Progression Using Paper Spray Ionization Mass Spectrometry

5. HPLC Isolation and Mass Spectrometric Characterization of Two Isomers of Thymine Glycols in Oligodeoxynucleotides