Synthesis and antibacterial activity studies <i>in vitro</i> of indirubin-3′-monoximes-Reference-Cited by-同舟云学术

Synthesis and antibacterial activity studies in vitro of indirubin-3′-monoximes

Published:2022 Issue:38 Volume:12 Page:25068-25080
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Yang Fen-Fen¹,Shuai Ming-Shan¹,Guan Xiang¹,Zhang Mao¹,Zhang Qing-Qing¹,Fu Xiao-Zhong¹,Li Zong-Qin²,Wang Da-Peng³,Zhou Meng¹,Yang Yuan-Yong¹^ORCID,Liu Ting¹,He Bin¹^ORCID,Zhao Yong-Long¹^ORCID

Affiliation:

1. State Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, and Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang 550004, People's Republic of China

2. Department of Neurology, Sichuan Mianyang 404 Hospital, Mianyang, 621000, People's Republic of China

3. Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, 550025, People's Republic of China

Abstract

In this work, based on the unique scaffold of indirubin, we synthesized 29 indirubin-3′-monoximes and preliminarily evaluated their antibacterial activities, especially against S. aureus.

Funder

Health Commission of Guizhou Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA01035F

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