Portable and benchtop Raman spectrometers coupled to cluster analysis to identify quinine sulfate polymorphs in solid dosage forms and antimalarial drug quantification in solution by AuNPs-SERS with MCR-ALS-Reference-Cited by-同舟云学术

Portable and benchtop Raman spectrometers coupled to cluster analysis to identify quinine sulfate polymorphs in solid dosage forms and antimalarial drug quantification in solution by AuNPs-SERS with MCR-ALS

Published:2020 Issue:18 Volume:12 Page:2407-2421
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Mazivila Sarmento J.¹²³⁴⁵^ORCID,Nogueira Helena I. S.⁶⁷⁸⁹^ORCID,Páscoa Ricardo N. M. J.¹⁰¹¹¹²¹³⁴^ORCID,Ribeiro David S. M.¹⁰¹¹¹²¹³⁴^ORCID,Santos João L. M.¹⁰¹¹¹²¹³⁴^ORCID,Leitão João M. M.²¹³¹⁴¹⁵⁹^ORCID,Esteves da Silva Joaquim C. G.¹²³⁴⁵^ORCID

Affiliation:

1. Centro de Investigação em Química da Universidade do Porto (CIQ-UP)

2. Research Centre in Chemistry (CIQ-UP)

3. Faculty of Sciences

4. University of Porto

5. 4169-007 Porto

6. Department of Chemistry and CICECO

7. University of Aveiro

8. 3810-193 Aveiro

9. Portugal

10. LAQV, REQUIMTE

11. Laboratory of Applied Chemistry

12. Department of Chemical Sciences

13. Faculty of Pharmacy

14. University of Coimbra

15. 3000-548 Coimbra

Abstract

Raman spectrometers coupled to cluster analysis were able to identify two polymorphs of quinine sulfate in solid dosage forms. Gold nanoparticles-surface-enhanced Raman scattering with MCR-ALS was used to antimalarial drug quantification in solution.

Funder

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/AY/D0AY00693A

Reference49 articles.

1. Advances in surface-enhanced Raman spectroscopy for analysis of pharmaceuticals: A review

2. Chemometrics coupled to vibrational spectroscopy and spectroscopic imaging for the analysis of solid-phase pharmaceutical products: A brief review on non-destructive analytical methods

3. Recent advances in the applications of vibrational spectroscopic imaging and mapping to pharmaceutical formulations