NMR studies of group 8 metallodrugs: 187Os-enriched organo-osmium half-sandwich anticancer complex-Reference-Cited by-同舟云学术

NMR studies of group 8 metallodrugs: 187Os-enriched organo-osmium half-sandwich anticancer complex

Published:2021 Issue:37 Volume:50 Page:12970-12981
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Needham Russell J.¹^ORCID,Prokes Ivan¹^ORCID,Habtemariam Abraha¹^ORCID,Romero-Canelón Isolda¹^ORCID,Clarkson Guy J.¹^ORCID,Sadler Peter J.¹^ORCID

Affiliation:

1. Department of Chemistry, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK

Abstract

Synthesis of this 187Os-enriched organo-osmium azopyridine anticancer complex, has allowed determination of 187Os NMR J-couplings to ligand 1H and 13C, and the 187Os chemical shift. The complex was also characterised by X-ray crystallography and MS.

Funder

Engineering and Physical Sciences Research Council

FP7 Ideas: European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/DT/D1DT02213J

Reference56 articles.

1. Metallodrugs in Medicinal Inorganic Chemistry

2. C.Imberti and P. J.Sadler , in Adv. Inorg. Chem , ed. P. J. Sadler and R. van Eldik , Academic Press , 2020 , vol. 75 , pp. 3–56

3. R. J.Needham and P. J.Sadler , in The Periodic Table II: Catalytic, Materials, Biological and Medical Applications , ed. D. M. P. Mingos , Springer International Publishing , Cham , 2019 , pp. 175–201

4. Metallodrugs are unique: opportunities and challenges of discovery and development

5. E.Alessio and L.Messori , in Metallo-Drugs: Development and Action of Anticancer Agents , ed. S. Astrid , S. Helmut , F. Eva and K. O. S. Roland , De Gruyter , 2018 , pp. 141–170

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