Synthesis of PEG-dendron for surface modification of pancreatic islets and suppression of the immune response

Author:

Jeon Seong Ik12345ORCID,Jeong Jee-Heon6785,Kim Ju Eun12345,Haque Muhammad R.9345,Kim Jungahn1011125,Byun Youngro9345,Ahn Cheol-Hee12345

Affiliation:

1. Research Institute of Advanced Materials (RIAM)

2. Department of Materials Science and Engineering

3. Seoul National University

4. Gwanak-gu

5. Republic of Korea

6. College of Pharmacy

7. Yeungnam University

8. Gyeongsan-si

9. Research Institute of Pharmaceutical Science, College of Pharmacy

10. Department of Chemistry

11. Kyunghee University 26

12. Dongdaemun-gu

Abstract

A surface modification technology with dendritic-structured poly(ethylene glycol) to protect islets from the host immune system was proposed for pancreatic islet transplantation.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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