Magnesium salt promoted tandem nucleophilic addition–Oppenauer oxidation of aldehydes with organozinc reagents
Author:
Affiliation:
1. College of Chemistry and Chemical Engineering
2. Northwest Normal University
3. Lanzhou
4. China
5. Health Innovations Research Institute and School of Applied Sciences
6. RMIT University
7. Melbourne
8. Australia
Abstract
A facile synthesis of aromatic ketones via tandem nucleophilic addition–Oppenauer oxidation of aromatic aldehydes with organozinc reagents was demonstrated. Magnesium salt in situ generated via organozinc formation is a powerful promotor for this transformation.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01668E
Reference73 articles.
1. Stereocontrolled Domino Reactions
2. Domino reactions for the synthesis of bridged bicyclic frameworks: fast access to bicyclo[n.3.1]alkanes
3. Nickel-Catalyzed Three-Component Domino Reactions of Aryl Grignard Reagents, Alkynes, and Aryl Halides Producing Tetrasubstituted Alkenes
4. Highly Regioselective Three-Component Domino Heck–Negishi Coupling Reaction for the Functionalization of Purines at C6
5. Pd(OAc)2-catalyzed domino reactions of 1,2-dihaloarenes and 2-haloaryl arenesulfonates with Grignard reagents: efficient synthesis of substituted fluorenes
Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Recent advances in transition-metal-free conversion of aldehydes to ketones;Green Synthesis and Catalysis;2024-05
2. Catalytic Magnesium-Oppenauer Oxidation of Alcohols;Chemistry Letters;2022-04-05
3. Synthesis of 7-Chloroquinoline Derivatives Using Mixed Lithium-Magnesium Reagents;The Journal of Organic Chemistry;2021-09-23
4. Copper-Catalyzed Hydroalumination of Allenes with Diisobutylaluminum Hydride: Synthesis of Allylic Ketones with α-Quaternary Centers via Tandem Allylation/Oppenauer Oxidation;Organic Letters;2020-07-13
5. Investigation into an Unexpected Impurity: A Practical Approach to Process Development for the Addition of Grignard Reagents to Aldehydes Using Continuous Flow Synthesis;Organic Process Research & Development;2020-02-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3