Inhibition-mediated changes in prolyl oligopeptidase dynamics possibly related to α-synuclein aggregation-Reference-Cited by-同舟云学术

Inhibition-mediated changes in prolyl oligopeptidase dynamics possibly related to α-synuclein aggregation

Published:2022 Issue:7 Volume:24 Page:4366-4373
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Walczewska-Szewc Katarzyna¹^ORCID,Rydzewski Jakub¹^ORCID,Lewkowicz Aneta²^ORCID

Affiliation:

1. Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University in Toruń, 87-100 Toruń, Poland

2. Faculty of Mathematics, Physics and Informatics, Gdansk University, Wita Stwosza 57, 80-952 Gdańsk, Poland

Abstract

The formation of protein aggregates is one of the leading causes of neuronal malfunction and subsequent brain damage in many neurodegenerative diseases.

Funder

Uniwersytet Mikolaja Kopernika w Toruniu

Fundacja na rzecz Nauki Polskiej

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CP/D1CP05238A

Reference51 articles.

1. Leucylglycinamide Released from Oxytocin by Human Uterine Enzyme

2. Structure, Function and Biological Relevance of Prolyl Oligopeptidase

3. On the role of prolyl oligopeptidase in health and disease

5. New tricks of prolyl oligopeptidase inhibitors – A common drug therapy for several neurodegenerative diseases

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