An apolipoprotein-enriched biomolecular corona switches the cellular uptake mechanism and trafficking pathway of lipid nanoparticles-Reference-Cited by-同舟云学术

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An apolipoprotein-enriched biomolecular corona switches the cellular uptake mechanism and trafficking pathway of lipid nanoparticles

Published:2017 Issue:44 Volume:9 Page:17254-17262
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Digiacomo L.¹²³⁴⁵,Cardarelli F.⁶⁷⁸⁹⁴,Pozzi D.¹²³⁴^ORCID,Palchetti S.¹²³⁴^ORCID,Digman M. A.¹⁰¹¹¹²¹³¹⁴,Gratton E.¹⁰¹¹¹²¹³¹⁴,Capriotti A. L.¹⁵²¹⁶⁴,Mahmoudi M.¹⁷¹⁸¹⁹²⁰¹⁴^ORCID,Caracciolo G.¹²³⁴^ORCID

Affiliation:

1. Department of Molecular Medicine

2. Sapienza University of Rome

3. 00161 Rome

4. Italy

5. Department of Bioscience and Biotechnology

6. NEST

7. Istituto Nanoscienze

8. CNR and Scuola Normale Superiore

9. Pisa

10. Laboratory for Fluorescence Dynamics

11. Biomedical Engineering Department

12. University of California

13. Irvine

14. USA

15. Department of Chemistry

16. 00185 Rome

17. Department of Anesthesiology

18. Brigham and Women's Hospital

19. Harvard Medical School

20. Boston

Abstract

The biomolecular corona promotes a switch of both the cell entry mechanism and the intracellular dynamics of liposomes.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NR/C7NR06437C

Reference51 articles.

1. Liposome–protein corona in a physiological environment: Challenges and opportunities for targeted delivery of nanomedicines

2. The nanoparticle biomolecule corona: lessons learned – challenge accepted?

3. Crucial role of the protein corona for the specific targeting of nanoparticles

4. Nanomedicine delivery: does protein corona route to the target or off road?

5. The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery

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