Regioselective glucosylation of (+)-catechin using a new variant of sucrose phosphorylase from <i>Bifidobacterium adolescentis</i>-Reference-Cited by-同舟云学术

Regioselective glucosylation of (+)-catechin using a new variant of sucrose phosphorylase from Bifidobacterium adolescentis

Published:2023 Issue:11 Volume:21 Page:2307-2311
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Demonceaux Marie¹^ORCID,Goux Marine¹^ORCID,Hendrickx Johann¹,Solleux Claude¹,Cadet Frédéric²,Lormeau Émilie¹,Offmann Bernard¹,André-Miral Corinne¹^ORCID

Affiliation:

1. US2B, CNRS UMR 6286, Nantes University, Nantes 44300, France

2. Laboratory of Excellence LABEX GR, DSIMB, Inserm UMR S1134, University of Paris City and University of Reunion, Paris 75014, France

Abstract

A new BaSP variant Q345F/P134D controls (+)-catechin glucosylation regioselectivity by modifying stabilisation interactions in the catalytic pocket of the enzyme.

Funder

Université de Nantes

Conseil Régional des Pays de la Loire

European Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00191A

Reference23 articles.

1. Bioactive flavonoids in medicinal plants: Structure, activity and biological fate