A natural polymer-based hydrogel with shape controllability and high toughness and its application to efficient osteochondral regeneration

Author:

Yang Jueying1ORCID,Wang Hui1,Huang Weiting1,Peng Kelin12,Shi Rui3,Tian Wei3,Lin Lizhi4,Yuan Jingjing1,Yao Weishang1,Ma Xilan1,Chen Yu145ORCID

Affiliation:

1. School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China

2. Yangtze Delta Region Academy of Beijing Institute of Technology, Jiaxing 314019, China

3. Beijing Research Institute of Traumatology and Orthopaedics, Beijing Jishuitan Hospital, Beijing 100035, China

4. Institute of Engineering Medicine, Beijing Institute of Technology, Beijing 10081, China

5. Sports & Medicine Integration Research Center (SMIRC), Capital University of Physical Education and Sports, Beijing 100191, China

Abstract

A natural polymer-based hydrogel with solely physically crosslinking hierarchical chain entanglements is prepared for efficient osteochondral regeneration owing to its shape controllability and high toughness.

Funder

Beijing Municipal Health Commission

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrical and Electronic Engineering,Process Chemistry and Technology,Mechanics of Materials,General Materials Science

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