Determination of 12 anti-obesity drugs in human plasma by a 96-well protein precipitation plate using HPLC-MS-Reference-Cited by-同舟云学术

Determination of 12 anti-obesity drugs in human plasma by a 96-well protein precipitation plate using HPLC-MS

Published:2022 Issue:40 Volume:12 Page:26016-26022
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ping Tengteng¹,Zheng Min²,Zhang Pingping³,Yan Tianhao¹,Miao Xufeng⁴,Wang Ke⁵,Lian Kaoqi¹⁶^ORCID

Affiliation:

1. School of Public Health, Hebei Medical University, Shijiazhuang, 050017, China

2. Jinan Centre for Disease Control and Prevention, Jinan, 250000, China

3. Department of Reproductive Genetic Family, Hebei General Hospital, Shijiazhuang, Hebei, 050000, China

4. Physical Education Department, Hebei Medical University, Shijiazhuang, 050017, China

5. Shijiazhuang Centre for Disease Control and Prevention, Shijiazhuang, 050011, China

6. Hebei Key Laboratory of Environment and Human Health, Shijiazhuang, 050017, China

Abstract

A 96-well protein precipitation plate combined with HPLC-MS/MS was developed for the determination of 12 anti-obesity drugs in human plasma; the detection method showed high throughout and high sensitivity with suitable recovery.

Funder

Hebei Provincial Key Research Projects

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA03423A

Reference38 articles.

1. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults

2. Fast food consumption among young adolescents aged 12–15 years in 54 low- and middle-income countries

3. The emerging epidemic of obesity in developing countries

4. Obesity and Coronary Artery Disease: Evaluation and Treatment

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