Iterative multitarget evolution dramatically enhances the enantioselectivity and catalytic efficiency of Bacillus subtilis esterase towards bulky benzoate esters of dl-menthol-Reference-Cited by-同舟云学术

Iterative multitarget evolution dramatically enhances the enantioselectivity and catalytic efficiency of Bacillus subtilis esterase towards bulky benzoate esters of dl-menthol

Published:2016 Issue:7 Volume:6 Page:2370-2376
ISSN:2044-4753
Container-title:Catalysis Science & Technology
language:en
Short-container-title:Catal. Sci. Technol.

Author:

Gong Yi¹²³⁴⁵,Xu Guo-Chao¹²³⁴⁵,Chen Qi¹²³⁴⁵,Yin Jin-Gang¹²³⁴⁵,Li Chun-Xiu¹²³⁴⁵,Xu Jian-He¹²³⁴⁵

Affiliation:

1. Laboratory of Biocatalysis and Synthetic Biotechnology

2. State Key Laboratory of Bioreactor Engineering

3. Shanghai Collaborative Innovation Center for Biomanufacturing

4. East China University of Science and Technology

5. Shanghai 200237

Abstract

Structure-based directed evolution has been successfully applied to Bacillus subtilis esterase to produce a mutant with higher enantioselectivity and elevated efficiency.

Publisher

Royal Society of Chemistry (RSC)

Subject

Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CY/C5CY01723H

Reference30 articles.

1. Enzymatic Production of l-Menthol by a High Substrate Concentration Tolerable Esterase from Newly Isolated Bacillus subtilis ECU0554

2. Efficient production of l-menthol in a two-phase system with SDS using an immobilized Bacillus subtilis esterase

3. High-performance continuous operation for enanthioselective esterification of menthol by use of acid anhydride and free lipase in organic solvent

4. Enantioselective Hydrolysis ofd,l-Menthyl Benzoate toL-(-)-Menthol by RecombinantCandida rugosa Lipase LIP1

5. Enantioselective Hydrolysis of dl-Menthyl Benzoate by Cell-Free Extract of Newly Isolated Acinetobacter sp. ECU2040

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