Base-promoted, CBr4-mediated tandem bromination/intramolecular Friedel–Crafts alkylation of N-aryl enamines: a facile access to 1H- and 3H-indoles
Author:
Affiliation:
1. College of Pharmaceutical Engineering of Traditional Chinese Medicine
2. Tianjin University of Traditional Chinese Medicine
3. Tianjin 301617
4. P. R. China
5. State Key Laboratory of Component-Based Chinese Medicine
Abstract
In the presence of CBr4 and a suitable base, the cyclization reaction of N-aryl enamines proceeds with high efficiency leading to a series of 1H-indoles and 3H-indoles with moderate to good yields.
Funder
Tianjin Municipal Education Commission
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00731A
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