An upconversion nanoparticle-integrated fibrillar scaffold combined with a NIR-optogenetic strategy to regulate neural cell performance-Reference-Cited by-同舟云学术

An upconversion nanoparticle-integrated fibrillar scaffold combined with a NIR-optogenetic strategy to regulate neural cell performance

Published:2023 Issue:2 Volume:11 Page:430-440
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Wu Chengheng¹²^ORCID,Su Borui¹,Xin Nini¹,Tang Jiajia¹,Xiao Jiamei¹,Luo Hongrong¹,Wei Dan¹,Luo Fang³,Sun Jing¹,Fan Hongsong¹^ORCID

Affiliation:

1. National Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, Sichuan, China

2. Institute of Regulatory Science for Medical Devices, Sichuan University, Chengdu, 610065, Sichuan, China

3. The Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China

Abstract

By integrating upconversion nanoparticles (UCNPs) with a bioactive scaffold with an oriented fibrillar structure, the NIR-responsive neuro-matrix interface is generated to activate light-sensitive protein CatCh for optogenetic neurogenesis regulation.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D2TB02327J

Reference31 articles.

1. Neural tissue engineering options for peripheral nerve regeneration

2. Restoration of sensorimotor functions after spinal cord injury

3. High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor