Preventing SARS-CoV-2 infection using Fv-antibodies targeting the proprotein convertase (PPC) cleavage site-Reference-Cited by-同舟云学术

Preventing SARS-CoV-2 infection using Fv-antibodies targeting the proprotein convertase (PPC) cleavage site

Published:2024 Issue: Volume: Page:
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Jung Jaeyong¹,Sung Jeong Soo¹,Kwon Soonil¹,Bae Hyung Eun¹^ORCID,Kang Min-Jung²^ORCID,Jose Joachim³^ORCID,Lee Misu⁴⁵,Pyun Jae-Chul¹^ORCID

Affiliation:

1. Department of Materials Science and Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea

2. Korea Institute of Science and Technology (KIST), Seoul, 02456, Korea

3. Institute of Pharmaceutical and Medical Chemistry, Westfälischen Wilhelms-Universität Münster, Muenster, Germany

4. Division of Life Sciences, College of Life Science and Bioengineering, Incheon National University, Incheon, 22012, Korea

5. Institute for New Drug Development, College of Life Science and Bioengineering, Incheon National University, Incheon, 22012, Korea

Abstract

Fv-antibodies targeting the PPC region of SARS-CoV-2 to prevent infection, screened from an Fv-antibody library (displayed on outer membrane of E. coli cell).

Funder

Ministry of Health and Welfare

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MD/D4MD00552J

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