An ultra-sensitive colorimetric assay for reliable visual detection of telomerase activity-Reference-Cited by-同舟云学术

An ultra-sensitive colorimetric assay for reliable visual detection of telomerase activity

Published:2017 Issue:17 Volume:142 Page:3235-3240
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Wang Yaocai¹²³⁴⁵,Yang Luzhu¹²³⁴⁵,Wang Yanjun¹²³⁴⁵,Liu Wei¹²³⁴⁵,Li Baoxin¹²³⁴⁵,Jin Yan¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Applied Surface and Colloid Chemistry

2. Ministry of Education

3. Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province

4. School of Chemistry and Chemical Engineering

5. Shaanxi Normal University

Abstract

We proposed a sensitive colorimetric assay for detecting telomerase activity. The telomerase activity of 5 and 20 HeLa cell lysates can be detected via UV-vis spectroscopy and the naked eye, respectively.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/AN/C7AN00950J

Reference21 articles.

1. Telomerase and cancer therapeutics

2. Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA

3. Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

4. Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP)

5. PCR-free and label-free fluorescent detection of telomerase activity at single-cell level based on triple amplification

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