Aptamer–gold nanoparticle conjugates for the colorimetric detection of arboviruses and vector mosquito species

Author:

Bosak Alexander12345ORCID,Saraf Nileshi67834,Willenberg Alicia12345,Kwan Michael W. C.12345,Alto Barry W.910111213,Jackson George W.14155,Batchelor Robert H.14155,Nguyen-Huu Truong D.14155,Sankarapani Vinoth14155,Parks Griffith D.162345,Seal Sudipta67834ORCID,Willenberg Bradley Jay12345

Affiliation:

1. Department of Internal Medicine

2. College of Medicine

3. University of Central Florida

4. Orlando

5. USA

6. Advanced Materials Processing and Analysis Center

7. Nanoscience and Technology Center

8. Department of Materials Science and Engineering

9. Department of Entomology and Nematology

10. Florida Medical Entomology Laboratory

11. University of Florida

12. IFAS

13. Vero Beach

14. Base Pair Biotechnologies, Inc.

15. Pearland

16. Burnett School of Biomedical Sciences

Abstract

Colorimetric detection of arboviruses and vector mosquito species. (A) Aptamer-gold nanoparticle conjugates, (B) mosquito salivary protein, (C) Zika envelope protein, (D) visible color change, (E) imbibed diagnostic and (F) diagnostic cards.

Funder

Florida Department of Agriculture and Consumer Services

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference40 articles.

1. Pan American Health Organization and World Health Organization , Zika - Epidemiological Report. United States of America , PAHO/WHO , Washington, D.C. , June 2017

2. Zika Virus Associated with Microcephaly

3. European Centre for Disease Prevention and Control , Rapid risk assessment: Zika virus epidemic in the Americas: potential association with microcephaly and Guillain-Barré syndrome , ECDC , Stockholm , 10 December 2015

4. Exploiting mosquito sugar feeding to detect mosquito-borne pathogens

5. S.Seal and B. J.Willenberg , Colorimetric Sensor Devices Using Aptamer-Gold Nanoparticle Conjugates for Field Surveillance of Mosquito-Borne Diseases. FDACS 2015 Final Report. Contract #022392 , retrived from FDACS website: https://www.freshfromflorida.com/content/download/73603/2112338/Willenberg_Colorimetric_Sensor_Device_Final_Report , accessed September 14th, 2018

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