Ecklonia radiata extract containing eckol protects neuronal cells against Aβ1–42 evoked toxicity and reduces aggregate density-Reference-Cited by-同舟云学术

Ecklonia radiata extract containing eckol protects neuronal cells against Aβ1–42 evoked toxicity and reduces aggregate density

Published:2020 Issue:7 Volume:11 Page:6509-6516
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Shrestha Srijan¹²³⁴⁵^ORCID,Zhang Wei⁶⁷⁸⁹¹⁰,Begbie Alexander J.¹¹¹²⁴⁵⁷,Pukala Tara L.¹¹¹²⁴⁵⁷^ORCID,Smid Scott D.¹²³⁴⁵^ORCID

Affiliation:

1. Discipline of Pharmacology

2. Adelaide Medical School

3. Faculty of Health Sciences

4. The University of Adelaide

5. Adelaide

6. Centre for Marine Bioproducts Development (CMBD)

7. Australia

8. Medical Biotechnology

9. College of Medicine and Public Health

10. Flinders University

11. Discipline of Chemistry

12. Faculty of Sciences

Abstract

Ecklonia radiata extract and phlorotannin fraction containing predominantly eckol-type phlorotannins inhibited the cytotoxicity of Aβ_1–42 in neuronal PC-12 cells and evoked a reduction in the density of Aβ_1–42 aggregates.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/FO/D0FO01438A

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