An acid-catalyzed 1,4-addition isocyanide-based multicomponent reaction in neat water-Reference-Cited by-同舟云学术

An acid-catalyzed 1,4-addition isocyanide-based multicomponent reaction in neat water

Published:2020 Issue:12 Volume:22 Page:3716-3720
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Lei Jie¹²³⁴⁵,Li Yong¹²³⁴⁵,Xu Jia¹²³⁴⁵,Tang Dian-Yong¹²³⁴⁵^ORCID,Shao Jing-Wei⁶¹⁷⁸⁹,Li Hong-yu⁶¹⁷⁸⁹,Chen Zhong-Zhu¹²³⁴⁵,Xu Zhi-Gang¹²³⁴⁵^ORCID

Affiliation:

1. College of Pharmacy

2. National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics

3. Chongqing Key Laboratory of Kinase Modulators as Innovative Medicine

4. Chongqing University of Arts and Sciences

5. Chongqing 402160

6. Department of Pharmaceutical Sciences

7. University of Arkansas for Medical Sciences

8. Little Rock

9. USA

Abstract

A 1,4-addition isocyanide-based three-component reaction was developed to synthesis chromanones derivatives with a green protocol, such as water solvent, simple operation, short reaction times, excellent yields and atom economy.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/GC/D0GC00652A

Reference46 articles.

1. To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis

2. Recent applications of multicomponent reactions in medicinal chemistry

3. Recent advances in multicomponent reactions involving carbohydrates

4. Recent Developments in the Isonitrile‐Based Multicomponent Synthesis of Heterocycles

5. Recent advances in the development of polycyclic skeletons via Ugi reaction cascades

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