Quantification of a mercapturate metabolite of the biocides methylisothiazolinone and chloromethylisothiazolinone (“M-12”) in human urine using online-SPE-LC/MS/MS-Reference-Cited by-同舟云学术

Quantification of a mercapturate metabolite of the biocides methylisothiazolinone and chloromethylisothiazolinone (“M-12”) in human urine using online-SPE-LC/MS/MS

Published:2021 Issue:15 Volume:13 Page:1847-1856
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Schettgen Thomas¹²³⁴⁵^ORCID,Bertram Jens¹²³⁴⁵,Weber Till⁶⁷⁵,Kraus Thomas¹²³⁴⁵,Kolossa-Gehring Marike⁶⁷⁵

Affiliation:

1. Institute for Occupational, Social and Environmental Medicine

2. Medical Faculty

3. RWTH Aachen University

4. D-52074 Aachen

5. Germany

6. German Environment Agency (UBA)

7. Berlin

Abstract

A first report on a urinary mercapturate metabolite of the biocides methylisothiazolinone and chloromethylisothiazolinone in urine samples of the general population.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/AY/D1AY00183C

Reference28 articles.

1. Scientific Committee on Consumer Safety (SCCS) , 2010. Opinion on the Mixture of 5-Chloro-2-Methylisothiazolin-3(2h)-One and 2-Methylisothiazolin-3(2h)-One (COLIPA No. P56), Submission II (Sensitation Only), SCCS 1238/09, Adopted during the 5th Plenary Meeting of 8 December 2009 . https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_009.pdf , last accessed: Nov. 2020

2. Preservation of products with MCI/MI in Switzerland

3. Emission of Isothiazolinones from Water-Based Paints

4. Occurrence and concentrations of isothiazolinones in detergents and cosmetics in Switzerland

5. Final Report of the Safety Assessment of Methylisothiazolinone

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