Organocatalytic, enantioselective synthesis of benzoxaboroles via Wittig/oxa-Michael reaction Cascade of α-formyl boronic acids-Reference-Cited by-同舟云学术

Organocatalytic, enantioselective synthesis of benzoxaboroles via Wittig/oxa-Michael reaction Cascade of α-formyl boronic acids

Published:2017 Issue:4 Volume:8 Page:3026-3030
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Hazra Gurupada¹²³⁴,Maity Sanjay¹²³⁴,Bhowmick Sudipto¹²³⁴,Ghorai Prasanta¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Indian Institute of Science Education and Research Bhopal

3. Bhopal-462066

4. India

Abstract

An enantioselective synthesis of 3-substituted benzoxaboroles has been developed using organocatalysts with good to excellent enantioselectivities (up to 99%). The resulting benzoxaboroles were converted to the chiral β-hydroxy ketones without affecting the enantioselectivity.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C6SC04522G

Reference69 articles.

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4. Antibiotikaresistenzen gezielt überwinden

5. Inhibiting the β-Lactamase of Mycobacterium tuberculosis (Mtb) with Novel Boronic Acid Transition-State Inhibitors (BATSIs)

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