Simultaneous detection of two subtypes of extracellular vesicles using ultrabright fluorescent nanosphere-based test strips

Author:

Li Zhi-Hua1,Liu Xing-Chi2,Wang Dan1,Zhang Zhi-Ling1ORCID,Chen Gang2345,Yu Zi-Li23,Tian Zhi-Quan16ORCID

Affiliation:

1. College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China

2. State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, China

3. Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan 430079, China

4. TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan 430071, China

5. Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan 430071, China

6. Key Laboratory of Environmental Engineering and Pollution Control on Plateau (Tibet Autonomous Region), School of Ecology and Environment, Tibet University, Lhasa 850000, China

Abstract

In recent years, the cargo profiles of extracellular vesicles (EVs), which were inherited from their parent cells, have emerged as a reliable biomarker for liquid biopsy (LB) in disease diagnosis, prognosis, and treatment monitoring.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

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