Interstrand DNA covalent binding of two dinuclear Ru(ii) complexes. Influence of the extra ring of the bridging ligand on the DNA interaction and cytotoxic activity-Reference-Cited by-同舟云学术

Interstrand DNA covalent binding of two dinuclear Ru(ii) complexes. Influence of the extra ring of the bridging ligand on the DNA interaction and cytotoxic activity

Published:2017 Issue:11 Volume:46 Page:3611-3622
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Lozano Héctor J.¹²³⁴,Busto Natalia¹²³⁴,Espino Gustavo¹²³⁴,Carbayo Arancha¹²³⁴,Leal José M.¹²³⁴,Platts James A.⁵⁶⁷⁸,García Begoña¹²³⁴^ORCID

Affiliation:

1. Chemistry Deparment

2. University of Burgos

3. 09001 Burgos

4. Spain

5. School of Chemistry

6. University of Cardiff

7. Cardiff

8. UK

Abstract

The quinones naphthazarin and quinizarin intercalate into DNA whereas their p-cymene di-ruthenium(ii) complexes bind covalently via interstrand crosslinking.

Funder

Consejería de Educación, Junta de Castilla y León

Ministerio de Economía y Competitividad

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/DT/C6DT04888A

Reference59 articles.

1. Metallodrugs in Medicinal Inorganic Chemistry

2. Medicinal Properties of Organometallic Compounds