A cannabidiol-loaded Mg-gallate metal–organic framework-based potential therapeutic for glioblastomas

Author:

Sharma Anu12345ORCID,Kumar Abhishek456ORCID,Li Changning456ORCID,Panwar Hazari Puja7893,Mahajan Supriya D.101112135ORCID,Aalinkeel Ravikumar101112135ORCID,Sharma Rakesh Kumar123,Swihart Mark T.456145ORCID

Affiliation:

1. Department of Chemistry

2. University of Delhi

3. India

4. Department of Chemical and Biological Engineering

5. University at Buffalo

6. USA

7. Division of Cyclotron and Radiopharmaceutical Sciences

8. Institute of Nuclear Medicine and Allied Sciences

9. Delhi

10. Department of Medicine

11. Division of Allergy

12. Immunology and Rheumatology

13. Jacobs School of Medicine and Biomedical Sciences

14. RENEW Institute

Abstract

Anticancer effects of cannabidiol-loaded magnesium-gallate metal–organic framework were studied in a rat glioma cell line, revealing anti-inflammatory responses and triggering of apoptosis, suggesting promise for glioblastoma therapy.

Funder

Department of Science and Technology, Ministry of Science and Technology

National Institute on Drug Abuse

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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