A microfluidic device inspired by leaky tumor vessels for hematogenous metastasis mechanism research-Reference-Cited by-同舟云学术

A microfluidic device inspired by leaky tumor vessels for hematogenous metastasis mechanism research

Published:2023 Issue:7 Volume:148 Page:1570-1578
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Yin Shuqing¹^ORCID,Lu Ruoyu¹,Li Yang¹,Sun Dexian¹,Liu Chong¹²^ORCID,Liu Bo³^ORCID,Li Jingmin¹

Affiliation:

1. Key Laboratory for Micro/Nano Technology and System of Liaoning Province, Dalian University of Technology, Dalian, China

2. Key Laboratory for Precision and Non-traditional Machining Technology of Ministry of Education, Dalian University of Technology, Dalian, China

3. School of Biomedical Engineering, Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, Dalian University of Technology, Dalian, China

Abstract

Exogenous chemotaxis under the concentration gradient of growth factors (CGGF) is demonstrated as a mechanism of hematogenous metastasis. A bionic microfluidic device inspired by the leaky tumor vessels is proposed to study the mechanism.

Funder

National Key Research and Development Program of China

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/AN/D2AN02081E

Reference34 articles.

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3. Openings between Defective Endothelial Cells Explain Tumor Vessel Leakiness

4. Cell migration microfluidics for electrotaxis-based heterogeneity study of lung cancer cells

5. Long-term migratory velocity measurements of single glioma cells using microfluidics

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