Quantitative characterization of conformational-specific protein–DNA binding using a dual-spectral interferometric imaging biosensor
Author:
Affiliation:
1. Department of Biomedical Engineering
2. Boston University
3. Boston, USA
4. Department of Electrical and Computer Engineering
5. School of Biological Sciences
6. Nanyang Technological University
7. Singapore 637551
Abstract
DNA-binding proteins play crucial roles in the maintenance and functions of the genome and yet, their specific binding mechanisms are not fully understood.
Funder
National Science Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science
Link
http://pubs.rsc.org/en/content/articlepdf/2016/NR/C5NR06785E
Reference52 articles.
1. DNA-Protein Interactions
2. From “Simple” DNA-Protein Interactions to the Macromolecular Machines of Gene Expression
3. The structure of DNA in the nucleosome core
4. Determining the specificity of protein–DNA interactions
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