Efficient production of (R)-3-TBDMSO glutaric acid methyl monoester by manipulating the substrate pocket of Pseudozyma antarctica lipase B
Author:
Affiliation:
1. School of Pharmaceutical Sciences
2. Jiangnan University
3. Wuxi
4. China
5. The Key Laboratory of Industrial Biotechnology
6. Ministry of Education
Abstract
Efficient production of optically pure (R)-3-substituted glutaric acid methyl monoesters, the multifunctional chiral building blocks used in the pharmaceutical industry, by manipulating the substrate pocket of Pseudozyma antarctica lipase B.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA06016E
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4. Impact of Leucine 278 Residue on Fatty Acid Length Specificity of <i>Candida antarctica</i> Lipase B
5. Stereoselective hydrolysis of triglycerides by animal and microbial lipases
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1. Application of Lipase B from Candida antarctica in the Pharmaceutical Industry;Industrial & Engineering Chemistry Research;2023-09-20
2. Biocatalytic Desymmetrization of Prochiral 3-Aryl and 3-Arylmethyl Glutaramides: Different Remote Substituent Effect on Catalytic Efficiency and Enantioselectivity;Advanced Synthesis & Catalysis;2018-10-22
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