Maternal organic selenium supplementation during gestation improves the antioxidant capacity and reduces the inflammation level in the intestine of offspring through the NF-κB and ERK/Beclin-1 pathways

Author:

Mou Daolin12345,Ding Dajiang12345,Yang Min12345,Jiang Xuemei12345,Zhao Lianpeng12345,Che Lianqiang12345ORCID,Fang Zhengfeng12345,Xu Shengyu12345,Lin Yan12345,Zhuo Yong12345,Li Jian12345,Huang Chao6274,Zou Yuanfeng6274,Li Lixia6274,Wu De12345,Feng Bin12345ORCID

Affiliation:

1. Animal Nutrition Institute

2. Sichuan Agricultural University

3. Chengdu

4. China

5. Key Laboratory of Animal Disease-Resistant Nutrition of Ministry of Education

6. College of Veterinary Medicine

7. Chengdu, Sichuan 611130

Abstract

Maternal HMSeBA supplementation during gestation improves offspring's intestinal antioxidant capacity and reduces the intestinal inflammation level by suppressing NF-κB and ERK/Beclin-1 signaling.

Funder

National Key Research and Development Program of China

Sichuan Agricultural University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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