Neutrophil trafficking on-a-chip: an in vitro, organotypic model for investigating neutrophil priming, extravasation, and migration with spatiotemporal control
Author:
Affiliation:
1. Department of Biomedical Engineering
2. University of Wisconsin – Madison
3. Madison
4. USA
5. University of Wisconsin Carbone Cancer Center
6. Department of Medical Microbiology and Immunology
7. Department of Pediatrics
Abstract
Her we report a new microfluidic technology designed to facilitate the study of neutrophil trafficking and priming using primary human cells with a high degree of spatiotemporal control.
Funder
National Institute of Allergy and Infectious Diseases
University of Wisconsin Carbone Cancer Center
National Cancer Institute
Congressionally Directed Medical Research Programs
Publisher
Royal Society of Chemistry (RSC)
Subject
Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering
Link
http://pubs.rsc.org/en/content/articlepdf/2019/LC/C9LC00562E
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1. Neutrophil recruitment and function in health and inflammation
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