Biological evaluation of dinuclear copper complex/dichloroacetic acid cocrystal against human breast cancer: design, synthesis, characterization, DFT studies and cytotoxicity assays

Author:

Usman Mohammad1234,Arjmand Farukh1234ORCID,Khan Rais Ahmad15678,Alsalme Ali15678,Ahmad Musheer9234,Tabassum Sartaj1234ORCID

Affiliation:

1. Department of Chemistry

2. Aligarh Muslim University

3. Aligarh-202002

4. India

5. College of Science

6. King Saud University

7. Riyadh 11451

8. Saudi Arabia

9. Department of Applied Chemistry

Abstract

Binuclear copper(ii) cocrystal “[Cu2(valdien)2⋯2Cl2CHCOOH],” 1 was synthesized from H2valdien scaffold and anticancer drug pharmacophore “dichloroacetic acid” embedded with two Cu(ii) connected via a hydrogen bonded network.

Funder

King Saud University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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