Fluorescence detection of telomerase activity in high concentration of cell lysates based on strand-displacement mediated recycling-Reference-Cited by-同舟云学术

Fluorescence detection of telomerase activity in high concentration of cell lysates based on strand-displacement mediated recycling

Published:2016 Issue:8 Volume:141 Page:2388-2391
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Li Xiaoqian¹²³⁴⁵,Wang Wei¹²³⁴⁵,Chen Yaoyao¹²³⁴⁵,Ding Caifeng¹²³⁴⁵

Affiliation:

1. Key Laboratory of Sensor Analysis of Tumor Marker

2. Ministry of Education

3. College of Chemistry and Molecular Engineering

4. Qingdao University of Science and Technology

5. Qingdao 266042

Abstract

Based on a template of the telomere elongation reaction of a telomerase substrate primer in the presence of telomerase, the strand-displacement process was used to prepare a fluorescence signal nanoprobe.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/AN/C5AN02560E

Reference26 articles.

1. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

2. The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

3. Biochemical aspects of telomerase function

4. Cell Cycle-Dependent Activation of Telomerase in Naturally Synchronized Culture of a True Slime Mold,Physarum polycephalum

5. A survey of telomerase activity in human cancer

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