Towards theory driven structure elucidation of complex natural products: mandelalides and coibamide A-Reference-Cited by-同舟云学术

Towards theory driven structure elucidation of complex natural products: mandelalides and coibamide A

Published:2016 Issue:24 Volume:14 Page:5826-5831
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Snyder Kevin M.¹²³⁴,Sikorska Justyna⁵²³⁴,Ye Tao⁶⁷⁸⁹¹⁰,Fang Lijing¹¹¹²¹³¹⁴⁹,Su Wu¹¹¹²¹³¹⁴⁹,Carter Rich G.¹²³⁴,McPhail Kerry L.⁵²³⁴,Cheong Paul H.-Y.¹²³⁴

Affiliation:

1. Department of Chemistry

2. Oregon State University

3. Corvallis

4. USA

5. Department of Pharmaceutical Sciences

6. Laboratory of Chemical Genomics

7. School of Chemical Biology and Biotechnology

8. Peking University Shenzhen Graduate School

9. Shenzhen

10. China

11. Guangdong Key Laboratory of Nanomedicine

12. Institute of Biomedicine and Biotechnology

13. Shenzhen Institutes of Advanced Technology

14. Chinese Academy of Sciences

Abstract

The effectiveness of computational tools in determining relative configurations of complex molecules is investigated, using natural products mandelalides A–D and coibamide A, towards a generalized recipe for the scientific community at large.

Funder

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB00707D

Reference19 articles.

1. Mandelalides A–D, Cytotoxic Macrolides from a New Lissoclinum Species of South African Tunicate

2. Coibamide A, a Potent Antiproliferative Cyclic Depsipeptide from the Panamanian Marine Cyanobacterium Leptolyngbya sp.

3. Efficient Synthesis and Stereochemical Revision of Coibamide A