Colibactin: understanding an elusive gut bacterial genotoxin-Reference-Cited by-同舟云学术

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Colibactin: understanding an elusive gut bacterial genotoxin

Published:2015 Issue:11 Volume:32 Page:1534-1540
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Balskus Emily P.¹²³⁴

Affiliation:

1. Department of Chemistry and Chemical Biology

2. Harvard University

3. Cambridge

4. USA

Abstract

This highlight reviews recent studies of colibactin, a structurally uncharacterized genotoxin synthesized by members of the human gut microbiota.

Funder

Kinship Foundation

Richard and Susan Smith Family Foundation

Damon Runyon Cancer Research Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/NP/C5NP00091B

Reference44 articles.

1. Specialized Metabolites from the Microbiome in Health and Disease

2. Small molecules from the human microbiota

3. A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals a Common Family of Antibiotics

4. Human and Plant Fungal Pathogens: The Role of Secondary Metabolites

5. The Chemical Arsenal of Burkholderia pseudomallei Is Essential for Pathogenicity

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