Synthesis, characterization, interactions with the DNA duplex dodecamer d(5′-CGCGAATTCGCG-3′)<sub>2</sub> and cytotoxicity of binuclear η<sup>6</sup>-arene-Ru(<scp>ii</scp>) complexes-Reference-Cited by-同舟云学术

Synthesis, characterization, interactions with the DNA duplex dodecamer d(5′-CGCGAATTCGCG-3′)₂ and cytotoxicity of binuclear η⁶-arene-Ru(ii) complexes

Published:2022 Issue:36 Volume:51 Page:13808-13825
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Georgakopoulou Christina¹,Thomos Dimitrios¹,Tsolis Theodoros¹,Ypsilantis Konstantinos¹,Plakatouras John C.¹²,Kordias Dimitris³⁴,Magklara Angeliki³⁴⁵,Kouderis Constantine¹,Kalampounias Angelos G.¹²,Garoufis Achilleas¹²^ORCID

Affiliation:

1. Department of Chemistry, University of Ioannina, GR-45110 Ioannina, Greece

2. University Research Center of Ioannina (URCI), Institute of Materials Science and Computing, Ioannina, Greece

3. Biomedical Research Institute-Foundation for Research and Technology, 45110 Ioannina, Greece

4. Laboratory of Clinical Chemistry, Faculty of Medicine, University of Ioannina, 45110 Ioannina, Greece

5. Institute of Biosciences, University Research Center of Ioannina (U.R.C.I.), Ioannina, Greece

Abstract

Novel binuclear organoruthenium complexes were synthesized and characterized, exhibiting significant DNA affinity and promising cytotoxicity.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/DT/D2DT02304K

Reference73 articles.

1. Synthetic metallomolecules as agents for the control of DNA structure

2. Metal complex interactions with DNA

3. DNA condensation induced by metal complexes

4. Stacking Interactions and DNA Intercalation

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