An aptasensor for the label-free detection of thrombin based on turn-on fluorescent DNA-templated Cu/Ag nanoclusters-Reference-Cited by-同舟云学术

An aptasensor for the label-free detection of thrombin based on turn-on fluorescent DNA-templated Cu/Ag nanoclusters

Published:2020 Issue:58 Volume:10 Page:35374-35380
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhang Baozhu¹²³,Wei Chunying⁴⁵⁶⁷³^ORCID

Affiliation:

1. College of Chemistry and Chemical Engineering

2. Jinzhong University

3. P. R. China

4. Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education

5. Institute of Molecular Science

6. Shanxi University

7. Taiyuan 030006

Abstract

A highly sensitive thrombin aptasensor was constructed based on the alteration of the aptamer conformation induced by the target recognition and the turn-on fluorescence due to the proximity of two darkish DNA-templated copper/silver nanoclusters (DNA-Cu/Ag NCs).

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA04609D

Reference55 articles.

1. A colorimetric aptamer biosensor based on cationic polymer and gold nanoparticles for the ultrasensitive detection of thrombin

2. An affinity capture involved enzymatic assay for thrombin by using peptide aptamers as affinity ligands on magnetic beads

3. Electrochemiluminescence Aptamer Biosensor for Detection of Thrombin Based on CdS QDs/ACNTs Electrode