Copper catalyzed cyano-sulfonylation of allenes via the insertion of sulfur dioxide toward the synthesis of (E)-α-cyanomethyl vinylsulfones

Author:

Li Yue1,Zhang Xuemei1,Lian Zhong1ORCID

Affiliation:

1. Department of Dermatology, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, P.R. China

Abstract

An efficient and practical method for highly regio- and stereo-selective cyanosulfonylation of allenes by inserting sulfur dioxide to synthesize useful (E)-α-cyanomethyl vinylsulfones has been explored.

Funder

Thousand Young Talents Program of China

Sichuan Province Science and Technology Support Program

West China Hospital, Sichuan University

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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