ATP regeneration by a single polyphosphate kinase powers multigram-scale aldehyde synthesisin vitro-Reference-Cited by-同舟云学术

ATP regeneration by a single polyphosphate kinase powers multigram-scale aldehyde synthesisin vitro

Published:2021 Issue:2 Volume:23 Page:828-837
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Tavanti Michele¹²³⁴⁵^ORCID,Hosford Joseph¹²³⁴⁵,Lloyd Richard C.⁶²³⁴⁵,Brown Murray J. B.¹²³⁴⁵

Affiliation:

1. Synthetic Biochemistry

2. Medicinal Science and Technology

3. Pharma R&D GlaxoSmithKline Medicines Research Centre

4. Stevenage SG12NY

5. UK

6. Chemical Development

Abstract

Towards scalable ATP recycling: a newly identified PPK2-III biocatalyst unlocked fullyin vitromultigram-scale aldehyde synthesis employing a carboxylic acid reductase.

Funder

Horizon 2020 Framework Programme

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/GC/D0GC03830J

Reference67 articles.

1. Emerging Enzymes for ATP Regeneration in Biocatalytic Processes

2. Round, round we go – strategies for enzymatic cofactor regeneration

3. Large-scale enzymic synthesis with cofactor regeneration: glucose 6-phosphate

4. Enzymatic synthesis of arginine phosphate with coupled ATP cofactor regeneration

5. Creatine Phosphate−Creatine Kinase in Enzymatic Synthesis of Glycoconjugates

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