Cleaving DNA-model phosphodiester with Lewis acid–base catalytic sites in bifunctional Zr

Cleaving DNA-model phosphodiester with Lewis acid–base catalytic sites in bifunctional Zr–MOFs

Published:2019 Issue:23 Volume:48 Page:8044-8048
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Zhou Ying-Hua¹²³⁴⁵^ORCID,Zhang Zhiyan¹²³⁴⁵,Patrick Margaret⁶⁷⁸,Yang Fan⁶⁷⁸,Wei Rangling¹²³⁴⁵,Cheng Yong¹²³⁴⁵,Gu Jing⁶⁷⁸^ORCID

Affiliation:

1. The Key Laboratory of Functional Molecular Solids

2. Ministry of Education

3. Anhui Laboratory of Molecule-Based Materials (State Key Laboratory Cultivation Base)

4. College of Chemistry and Materials Science

5. Anhui Normal University

6. Department of Chemistry and Biochemistry San Diego State University

7. San Diego State University

8. USA

Abstract

UiO-67-bpydc-Zn with isolated multi-catalytic active sites was fabricated as a catalyst for the hydrolysis of bis(p-nitrophenyl) phosphate as a DNA model. The enhanced activity may likely be attributed to the cooperation effects between the Lewis acid from the zirconium center at the node and the zinc hydroxide Lewis base in the linkers.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Anhui Province

San Diego State University

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/DT/C9DT00246D

Reference43 articles.